What is PRP?
Platelet Rich Plasma (PRP) is blood plasma that contains a concentrated source of autolo-gous platelets. The platelets collected in PRP may Be activated exogenously by adding thrombin and/or calcium chloride or by placing under the skin tissue which induces the re-lease of these factors by degranulation of the alpha granules produced. Meaning when injected within tissue the platelets will release of growth factors by the thrombocytes and leukocytes.
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What do growth factors do?
Growth factors will then bind to growth receptors in the area of injection, additional stem cells will be attracted to the area – stem cell proliferation and mitosis begins. Regeneration occurs within the tissues and fibrils en-sues.
What is PRP used for?
PRP can be used for various of indications due to its high growth factors and additional stem cells will be attracted to the area – stem cell proliferation and mitosis begins. Regeneration occurs within the tissues and fibrils ensues. PRP works well with:
Indications:
- Collagen production
- Damaged skin
- Medical tendinpathies,
- Bone/joint Regeneration
- Wound Healing
Are all PRP the same?
Why Double Spin is more Superior than Single spin?
Studies have shown that the quantitative and qualitative power of platelets and progenitor stem cell concentrate are optimal when double centrifugation is used.
There are (2) FDA approved preparation methods to create the PRP solution which are either single spin or dual spin technologies. The double centrifuge protocol yields a significant higher concentration of platelets (3:1) and has other advantages. Total cells delivered (CD34+) using dual spin technologies are considerably higher and is needed since CD34+ are markers for stem
cells and will reside in the mononuclear fraction. In essence there is not only a large concentration of stem cells but also stem cell markers when using dual spin technologies.
- Single-spin PRP devices will produce lower (2.5-3x) baseline concentrations.
- Double -Spin Devices will yield higher baseline concentrations of platelets (5-9x).
